New research from the University of Rochester Medical Center says if you're hurting from getting the flu shot, stay away from over-the-counter pain relievers.

The research headed by Richard Phipps, Ph.D., professor of Environmental Medicine, Microbiology and Immunology and Pediatrics says pain relievers could dilute the power of the flu shots.

Dr. Phipps says, "We have studied this question using virus particles, live virus, and different kinds of pain relievers, in human blood samples and in mice -- and all of our research shows that pain relievers interfere with the effect of the vaccine."

Taking Advil or Tylenol as soon as you feel pain would have the most detrimental effect on the immune system.

Similar results were found in a study in the Czech Republic just two weeks ago.